Chiara D'Aprile
postdoctoral researcher
Milano,Milano
Summary
Skilled researcher enthusiastic about supporting advancements in life sciences, with a background in biochemistry and molecular biology. Passionate about increasing knowledge to drive growth and needed improvements. Ready to apply knowledge and 4 years of experience in research.
Overview
1
1
year of professional experience
Work History
Postdoctoral fellow
Biology of Myelin Unit
04.2023 - 12.2023
Research activity in the fields of molecular biology, PI D'Antonio Maurizio
In the context of the Unfolded Protein Response (UPR) modulation, I tested a selective ATF6 activating compound AA147 in an animal model of Charcot Marie Toot disease type CMT1B _S63del mouse model (FVB background)
Education
PhD - Translational Medicine, XXXV cycle
University of Milan
04.2023
Master's - Biology applied to Biomedical research
University of Milan
10.2019
Bachelor's - Biological Sciences
University of Genoa
03.2017
Scientific High school Certificate -
Liceo Scientifico PALLI
07.2011
Skills
- Research Protocols
- Specific Research Projects
- Research Procedures
- Adaptability
- Problem Solving
- Scientific Presentations
- Teaching Experience
- Literature Review
- Scientific Communication
- Critical Thinking
- Experimental Design
- Data Analysis
- Lab Management
- Data Science
- Scientific Writing
- Research
- Relationship Management
- Interpersonal Communication
- Microsoft Excel
- Tutoring and Mentoring
- Student Tutoring
- Microsoft Office
- Coaching and Training
- Lab Experiments and Research
- Chemical and Molecular Analysis
- Genetic diseases
- Scientific Principles Application
- Molecular Biology
- Reverse Transcriptases
- Experiment Protocol Development
- Protein Purification
- Protein Characterization
- Microsoft Word
- Lyophilization
- Research and Publication
Tecniques
Cell Culture; Metabolic Labeling Experiment; Lipids Extraction; Lipids Partitioning; High-Performance Thin-Layer Chromatography (HPTLC); Protein Extraction and Quantification with SDS-PAGE Electrophoresis and Western Blot; Immunofluorescence; Electrospray Ionization Mass Spectrometry (ESI-MS); Capillary Electrophoresis (CE); High-Performance Liquid Chromatography (HPLC).
Animal Handling, IP Injection, and Harvesting of Organs (Sciatic Nerves, Kidney, Liver, and Heart). DNA extraction; PCR; RNA extraction; Reverse transcriptase (RT-q-PCR); TaqMan gene expression; DRG culture from an E15.5 mouse embryo;
Linkedin Profile
https://www.linkedin.com/in/chiara-d-aprile-693976b2
Personal Information
- Date of Birth: 05/26/1992
- Gender: Female
- Nationality: Italian
Awards
ESN Young Members’ Symposia, ESN Meeting, St. Petersburg, Russia, May 22-25, 2022
Publications
Lipid rafts as platforms for sphingosine 1-phosphate metabolism and signalling, 2021, 10.1016/j.cellsig.2021.109929, https://pubmed.ncbi.nlm.nih.gov/33493577/; Analysis of sphingolipids pattern in microglia after treatment with a remyelinating promoting antibody, 2021, Poster Abstract_ B17_ ASN Neuro 1–154, 10.1177/17590914211039028, journals.sagepub.com/home/asn; Sphingolipid-dependent membrane organization and signaling orchestrating myelin repair, 2021, Poster Abstract_ C02_ ASN Neuro 1–154, 10.1177/17590914211039028, journals.sagepub.com/home/asn
Conferences
ISN-APSN meeting 2022, Honolulu, USA; 30th Gordon Research Conference on Glycolipid and Sphingolipid Biology, Renaissance Tuscany Il Ciocco, Lucca (Barga), LU, Italy; 32nd National meeting of PhD students in Biochemical Sciences, Brallo di Pregola, Pavia, Italy; ASN 2021 Meeting; 1st Virtual Conference of the European Society for Neurochemistry; 11th INTERNATIONAL CERAMIDE CONFERENCE; 3rd BraYnstorming Research Assembly for Young Neuroscientist.
Timeline
Postdoctoral fellow
Biology of Myelin Unit
04.2023 - 12.2023
PhD - Translational Medicine, XXXV cycle
University of Milan
Master's - Biology applied to Biomedical research
University of Milan
Bachelor's - Biological Sciences
University of Genoa
Scientific High school Certificate -
Liceo Scientifico PALLI
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