Giacomo Guidi

Gynecologic-oncology dedicated final-year resident at Fondazione Policlinico Universitario Agostino Gemelli – IRCCS, concluding residency training on November 3, 2026. Graduated from "Sapienza, University of Rome" with a thesis focused on advanced ovarian cancer. Possesses extensive surgical experience in gynecologic oncology and complex pelvic procedures, further refined through a rotation at Candiolo Cancer Institute and professional courses. Proficient in minimally invasive and robotic surgery, specifically on Da Vinci Single Port platform, and actively involved in clinical trials. Demonstrated commitment to translational research—in particular patient-derived organoids and liquid biopsy—and a record of academic presentations at international congresses such as ESGO congresses. Committed to a multidisciplinary approach that integrates advanced surgical techniques with innovative research to optimize outcomes for oncological patients.

• Certificate of Presenting Author: ESGO 2026-Poster Walk, international congress
• INTERACT EUROPE 100, ISCT (ESO – Heidelberg University Hospital – ACOE): Inter-specialty cancer training (European Union co-founded project).
• “Leadership in Clinical Research: path to become Principal Investigator” certificate: course at Candiolo Cancer Institute, IRCCS, on the following topics: Clinical trial design and planning, Trial submission and start-up phase, Requirements for centers participating in non-profit Phase 1 trials, Trial conduct, Data accuracy and quality, Responsibilities of a principal investigator in conducting a trial, Trial closure and publication
• Da Vinci Single Port (SP): First Assistant Certificate.
• GESEA 1 (ESGE Academy): General endoscopic knowledge and acquirement of basic endoscopic psychomotor skills.
• GESEA 2 (ESGE Academy): Knowledge and advanced psychomotor skills for endoscopic procedures.
• CMR-Versius Robotic System: First Assistant Certificate.
• ESGO-ENYGO Masterclass (2023): Masterclass in Gynaecological Oncology (in cooperation with ESO)
• Certificate of Presenting Author: Campus Bio-Medico University - Best of advanced pelvic surgery (2022), national course.
• Certificate of Presenting Author: SEGI (Italian society of endoscopic gynecology) national congress 2018 – Artificial intelligence: present applications and future perspectives.

1) Cattaneo CG, Musio D, Tanzi F, Guidi G, Palaia I, Tombolini V, DE Felice F. Synchronous Anal Canal Cancer and Cervical Cancer: Report of a Case and Management Implication. In Vivo. 2022 Sep-Oct;36(5):2521-2524. doi: 10.21873/invivo.12988. PMID: 36099119; PMCID: PMC9463915.

2) Bizzarri N, Capomacchia FM, Guidi G, Fragomeni SM, Garganese G, Fagotti A, Scambia G, Naldini A. How to Perform Bilateral Sentinel Lymph Node Biopsy in Vulvar Cancer with Indocyanine Green by Video-Endoscopic Approach. Ann Surg Oncol. 2025 Jun;32(6):4322-4323. doi: 10.1245/s10434-025-17022-4. Epub 2025 Mar 6. PMID: 40048028.

3) Guidi G, Vargiu V, Ammar S, Bizzarri N, Querleu D, Scambia G, Fanfani F. Radical hysterectomy and ovarian transposition during cesarean section for newly diagnosed cervical cancer in pregnancy. Int J Gynecol Cancer. 2025 Aug;35(8):101663. doi: 10.1016/j.ijgc.2025.101663. Epub 2025 Jan 25. PMID: 40057417.

4) Bizzarri N, Guidi G, Pavone M, Pedone Anchora L, Rychlik A, Goglia M, Fanfani F, Scambia G, Querleu D. Laparoscopic para-uterine lymphovascular tissue sentinel lymph node biopsy with indocyanine green in cervical cancer. Int J Gynecol Cancer. 2025 Nov;35(11):101744. doi: 10.1016/j.ijgc.2025.101744. Epub 2025 Feb 27. PMID: 40069071.

5) Bizzarri N, Capomacchia FM, Guidi G, Fragomeni S, Garganese G, Fagotti A, Scambia G, Naldini A. ASO Author Reflections: Minimally Invasive Approach for Bilateral Sentinel Node Using Indocyanine Green in Vulvar Cancer: Not Only a Technical Issue. Ann Surg Oncol. 2025 Aug;32(8):5626-5627. doi: 10.1245/s10434-025-17339-0. Epub 2025 Apr 17. PMID: 40244350.

6) Capomacchia FM, Alberghetti B, Guidi G, Fanfani F, Scambia G, Fagotti A, Turco LC. Single-port robotic fertility-sparing surgery for clear cell ovarian carcinoma. Int J Gynecol Cancer. 2025 Jun;35(6):101899. doi: 10.1016/j.ijgc.2025.101899. Epub 2025 Apr 22. PMID: 40367703.

7) Oliva R, De Rose AM, Ardito F, Guidi G, Certelli C, Bruno M, Fagotti A, Gallotta V. Three-dimensional reconstruction and laparoscopic liver resection for recurrent ovarian cancer: quaternary cytoreductive surgery. Int J Gynecol Cancer. 2025 Sep;35(9):101914. doi: 10.1016/j.ijgc.2025.101914. Epub 2025 May 16. PMID: 40413130.

8)D'Indinosante M, Guidi G, Giannarelli D, Diella C, Rosati A, Oliva R, Faustini AZ, Querleu D, Scambia G, Fagotti A. Laparoscopic tumor load as an independent prognostic marker in advanced ovarian cancer: a 3-year cohort study. Int J Gynecol Cancer. 2025 Aug;35(8):101965. doi: 10.1016/j.ijgc.2025.101965. Epub 2025 Jun 6. PMID: 40616863.

9)Guidi G, Naldini A, Garganese G, Fragomeni SM, Fagotti A, Bizzarri N. Endoscopic inguinal lymphadenectomy for vulvar cancer, is it feasible? Curr Opin Oncol. 2025 Sep 1;37(5):487-491. doi: 10.1097/CCO.0000000000001174. Epub 2025 Jul 22. PMID: 40704378; PMCID: PMC13237939.

10) Imterat M, Bizzarri N, Stern S, Guidi G, Brandt B, Criscione M, Matan L, Arrigo D, Haran TK, Saccus P, Prus D, Bruno M, Perri T, Fagotti A. Gliomatosis peritonei with ovarian teratoma: an international multicenter case series. Int J Gynecol Cancer. 2026 Jan;36(1):102720. doi: 10.1016/j.ijgc.2025.102720. Epub 2025 Oct 17. PMID: 41259847.

11) Turco LC, Alberghetti B, Cartia CF, Biscione A, Guidi G, Capomacchia FM, Droghetti A. Case Report: Thoracoscopic secondary cytoreductive surgery for high-grade serous ovarian cancer. Front Surg. 2026 Mar 5;13:1737893. doi: 10.3389/fsurg.2026.1737893. PMID: 41869399; PMCID: PMC12999868.

12) Arora L, Schötzau A, Bizzarri N, Guidi G, Fagotti A, Labidi-Galy I, Levy T, Heinzelmann-Schwarz V. Heterogeneity in Stage IV Ovarian Cancer: Survival Trends in Patients Presenting with Sister Mary Joseph’s Nodule. Cancers (Basel). 2026 Mar 10;18(6):897. doi: 10.3390/cancers18060897. PMID: 41899501.

• Dr. Guidi actively participates in the following clinical research protocols:
• DEBULK Trial (KGOG1047): Facilitated the preparation and ethical submission at Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome
• MISSION 2.0 (NCT07031908): cooperating in protocol preparation, submission procedures and data collection across Fondazione Policlinico Universitario Agostino Gemelli IRCCS and Candiolo Cancer Institute, IRCCS
• LANCE Trial (NCT04575935): cooperating in data collection and patient postoperative follow-up at Fondazione Policlinico Universitario Agostino Gemelli IRCCS.
• PROACTIVE and PROFILING protocol: actively collaborating with clinical data collection on translational activities involving patient-derived organoids, ctDNA, and CTCs (See scientific production)

1) Rosati, A., De Palma, A., Zampolini, A., Guidi, G., Pavone, M., Conte, C., ... & Fagotti, A. (2023). # 1025 Liver parenchymal infiltrative pattern in advanced ovarian cancer: topographic anatomy of disease distribution. International Journal of Gynecological Cancer, 33, A330-A331.

2) Rosati, A., Guidi, G., De Palma, A., Zampolini, A., Boccia, S., Conte, C., ... & Fagotti, A. (2023). # 1033 Laparoscopic interval debulking surgery: where do we stand and where do we need to go?. International Journal of Gynecological Cancer, 33, A51.

3) Rosati, A., Guidi, G., De Palma, A., Zampolini, A., Conte, C., Ghirardi, V., ... & Fagotti, A. (2024). 1094 Secondary cytoreductive surgery for type IV recurrent granulosa cell tumor according to gemelli anatomo-surgical classification of ovarian cancer metastases in the liver area. International Journal of Gynecological Cancer, 34, A68.

4) Rosati, A., Guidi, G., Zampolini, A., De Palma, A., Conte, C., Ghirardi, V., ... & Fagotti, A. (2024). 1099 Is it worth and feasible to apply nerve sparing principles to laparoscopic para-aortic lymphadenectomy?. International Journal of Gynecological Cancer, 34, A59.

5) Rosati, A., Pianese, G., Vargiu, V., Loverro, M., Lancellotti, G., Guidi, G., ... & Fagotti, A. (2025). ATLANTIS STUDY: AnaTomo-Surgical Classification And Role Of Thoracic Cytoreduction In Advanced Ovarian Cancer. International Journal of Gynecological Cancer, 35(2).

6) Guidi, G., Bruno, M., Figà, M., Filip, D. P., Capomacchia, F. M., Corrado, M., ... & Turco, L. C. (2026). Comprehensive clinico-pathologic and molecular characterization of female adnexal tumor of wolffian origin. International Journal of Gynecological Cancer, 36(2).

7) Filippo Maria Capomacchia, Maria Zanatta, Martina Corrado, Tiziana Venesio, Christopher Heeschen, Sara Gilardi, Chiara Reina, Berina Sabanovic, Maristella Bungaro, Giacomo Guidi, Giuseppe Dario Montana, Benedetta Alberghetti, Antonella Biscione, Camilla Nero, Vanesa Gregorc, Sabrina Arena, Denisa Petronela Filip, Anna Fagotti, Luigi Carlo Turco. "Diagnostic value of baseline circulating cell-free DNA and circulating tumor cells for predicting peritoneal disease burden in advanced ovarian cancer: preliminary results of a prospective pilot study." International Journal of Gynecological Cancer 36.2 (2026).

8) Filippo Maria Capomacchia, Martina Corrado, Maria Zanatta, Tiziana Venesio, Sara Gilardi, Maristella Bungaro, Giacomo Guidi, Giuseppe Dario Montana, Benedetta Alberghetti, Antonella Biscione, Camilla Nero, Vanesa Gregorc, Sabrina Arena, Denisa Filip, Anna Fagotti, Luigi Carlo Turco. "Preoperative circulating cell-free DNA as predictor of postoperative complications after primary and interval cytoreductive surgery for advanced ovarian cancer." International Journal of Gynecological Cancer 36.2 (2026).

9) Giada De Lazzari, Laura Bizzozzero, Keti Ilovska, Sara Erika Bellomo, Enrico Berrino, Jessica Erriquez, Giacomo Guidi, Filippo Maria Capomacchia, Martina Olivero, Luigi Carlo Turco, Caterina Marchiò, Sabrina Arena. "Exploiting patient-derived models to unveil replication stress vulnerabilities as effective therapeutic targets in gynecological cancers." International Journal of Gynecological Cancer 36.2 (2026).