Miriam Toffoli
Trieste
Profilo professionale
PhD candidate in Immunology with solid background in translational research and laboratory activities. Throughout doctoral work, gained extensive experience in handling patient biological samples with strict attention to traceability and regulatory compliance, developed advanced cellular models from literature protocols, and performed diagnostic support analyses. Demonstrated adaptability in learning new techniques across different laboratory environments, strong problem-solving abilities in protocol optimization, and capacity to work both independently and collaboratively within multidisciplinary teams. Proven organizational skills in managing multiple concurrent projects and coordinating laboratory workflows. Motivated to transition into biotech industry to apply research expertise and practical approach to innovative R&D projects.
Panoramica
6
6
years of professional experience
1
1
Certification
Esperienza lavorativa
PhD candidate and Research fellow
IRCCS Burlo Garofolo
Trieste
2022.10 - Current
- Conducted applied immunology research with direct relevance to reproductive medicine and clinical diagnostics
- Established and optimized a 3D organoid culture system by implementing protocols adapted from published literature
- Worked routinely with patient-derived biological samples, ensuring traceability, data integrity, and privacy compliance
- Contributed to experimental planning and execution across multiple parallel research projects in a multidisciplinary environment
- Supervised and trained 2 MSc students and 2 international Erasmus students in laboratory techniques, experimental design, and scientific communication
- Managed laboratory consumables and inventory, monitoring stock levels and coordinating procurement processes (supplier quotes, purchase orders) to support daily operations
- Presented research results at national and international scientific conferences to expert audiences
Visiting PhD Student
Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG)
Dresden
2025.07 - 2025.10
- Integrated new technical skills and methodologies into ongoing research within an international research environment
- Worked independently with specialized core facilities to perform advanced experimental procedures
- Coordinated project activities between home and host institutions
Junior Research Fellow
IRCCS Burlo Garofolo
Trieste
2020.05 - 2022.10
- Developed and optimized custom ELISA assays for quantifying complement factors in patient sera, systematically refining each step of the protocol to achieve reliable measurements
- Interpreted experimental results and communicated findings to researchers and clinicians, supporting translational and diagnostic applications
Istruzione
PhD Candidate - Immunology (School of Reproductive and Developmental biology)
University of Trieste
Trieste 2022 - 2026
Master's degree - Medical and diagnostic biotechnologies
University of Trieste
Trieste 2020 - 2022
Bachelor's degree - Biomedical Lab Technician
University of Trieste
Trieste 2016 - 2019
Competenze
Soft skills:
- Experimental problem-solving and systematic troubleshooting
- Ability to work effectively in cross-functional and multidisciplinary teams
- Strong adaptability and fast learning in dynamic research environments
- Clear scientific communication with both technical and non-technical stakeholders
- Critical thinking and data-driven decision making
- Experience in mentoring and training junior team members
Technical skills:
- Immunological assays - ELISA, flow cytometry, immunofluorescence, Western blot, antibody isolation
- Cell culture - 2D and 3D models, primary cells
- Histology - tissue embedding, sectioning, immunohistochemistry
- Molecular biology - RNA extraction, RT-qPCR
- Microscopy - confocal imaging, fluorescence microscopy
- Microbiology - bacterial and fungal culture, microbial identification
- Sample management - patient sample handling, traceability, privacy compliance
- Data analysis - GraphPad Prism, FlowJo, ImageJ, Microsoft Office
Language skills
Italiano
Native language
Inglese
Avanzato
Certificazioni
- Basic Flow Cytometry Course - Società italiana di citometria, 2024
- Radiation Safety and Protection Training - University of Trieste,2022
Selected publications
- C1q/gC1qR interaction promotes trophoblast invasion: insights from single-cell analysis and trophoblast organoid models (2026, under submission)
- A possible association between low MBL/lectin pathway functionality and microbiota dysbiosis in endometriosis patients. Life Sciences (2025)
- Endothelial cell supplementation promotes xenograft revascularization during short-term ovarian tissue transplantation. Bioactive Materials (2025)
- Proangiogenic properties of complement protein C1q can contribute to endometriosis. Frontiers in Immunology (2024)
Cronologia
Visiting PhD Student
Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG)
2025.07 - 2025.10
PhD candidate and Research fellow
IRCCS Burlo Garofolo
2022.10 - Current
Junior Research Fellow
IRCCS Burlo Garofolo
2020.05 - 2022.10
PhD Candidate - Immunology (School of Reproductive and Developmental biology)
University of Trieste
2022 - 2026
Master's degree - Medical and diagnostic biotechnologies
University of Trieste
2020 - 2022
Bachelor's degree - Biomedical Lab Technician
University of Trieste
2016 - 2019