MICHELA CARRARO

• Dec 2018 - Jun 2019: Maternity leave
• Aug 2023 – Jan 2024: Maternity leave

• TERAPIA GENICA E FARMACI A RNA NELLA MEDICINA DI PRECISIONE - MEDICINA E CHIRURGIA (sede di Padova) (2023-2026)
• Esercitazioni di PATOLOGIA GENERALE E FISIOPATOLOGIA - MEDICINA E CHIRURGIA (sede di Padova): 24 ore (2023-2026)
• PATOLOGIA GENERALE E MICROBIOLOGIA- INFERMIERISTICA (ABILITANTE ALLA PROFESSIONE SANITARIA DI INFERMIERE) (sede di Treviso): 40 ore (2023-2026)

• FIS3 grant, project entitled: Linking mitochondria function to motility: the ATP synthase as a molecular bridge. (1.098.000 EUR);
• “MARIA PAOLA BELLONI” award for Medical, Biomedical, and Pharmaceutical research. Alumni association, University of Padova (VII edizione, 2022)

• 2014 – current: Member of the Italian Group of Biomembranes and Bioenergetics (GIBB)
• 2023 – 2026: Member of the Biophysical Society (BPS)

2023 - current: Member of the Editorial Board of Pharmacological Research

2025 - current: Member of the Early Career Editorial Board of Cells

2024 – “Piccole menti in fermento”, activity for kids in the context of the Science4ALL for school (20/11/2024).

INVITED LECTURES

• 22nd European Bionenergetics Conference (August 2024, Innsbruck, Austria)
• Annual Meeting of the Biophysical Society, Mitochondria and Metabolism Subgroup Symposium (February 2024, Philadelphia, USA)
• International Conference on Cell Death and Disease (June 2017, Villa Vigoni, Como, Italy)
• Young Mito Investigator Symposium, Conference on Mitochondria in life, death and disease (September 2021, University of Cologne, Germany) [web conference]

ORAL PRESENTATIONS

• Cold Spring Harbor Asia Conference on Mitochondria and Metabolism in Health and Disease (October 13-17 2025, Suzhou, China)
• 21st European Bioenergetics Conference (August 2022 Aix-en-Provence, France)
• Cold Spring Harbor Asia Conference on Mitochondria and Metabolism in Health and Disease (November 2021, Suzhou, China) [web conference]
• Leducq International Network “Targeting Mitochondria to Treat Heart Disease” (September 2019, Portland, Oregon, USA)
• 20th European Bioenergetics Conference (August 2018, Budapest, Hungary)
• Leducq International Network “Targeting Mitochondria to treat Heart Disease” (April 2018, Barcelona, Spain)
• Organellar Channels and Transporters, Gordon Research Conference (August 2017, Mount Snow, West Dover VT, USA)
• Leducq International Network “Targeting Mitochondria to treat Heart Disease” (September 2017, Lyon, France)
• 18th European Bioenergetics Conference (July 2014 Lisbon, Portugal)
• Annual meeting of Biomembranes and Bioenergetics (June 2013, Padova, Italy)

• Carraro M, Gerle C and Bernardi P. The Mitochondrial Permeability Transition Pore: Past, Present and Future. Annual Review of Biophysics (2025) Dec 12. doi:10.1146/annurev-biophys-030722-020832.
• Tommasin L, Carrer A, Nata FB, Frigo E, Fogolari F, Lippe G, Carraro M (co-corresponding author), Bernardi P. Adenine nucleotide translocator and ATP synthase cooperate in mediating the mitochondrial permeability transition. Journal of Physiology. 2025 Jan 14. doi: 10.1113/JP287147. Epub ahead of print. PMID: 39808538.
• Coluccino G, Negro A, Filippi A, Bean C, Muraca VP, Gissi C, Canetti D, Mimmi MC, Zamprogno E, Ciscato F, Acquasaliente L, De Filippis V, Comelli M, Carraro M, Rasola A, Gerle C, Bernardi P, Corazza A, Lippe G. N-terminal cleavage of cyclophilin D boosts its ability to bind F-ATP synthase. Communications Biology. 2024 Nov 11;7(1):1486.
• Marcucci L, Nogara L, Canato M, Germinario E, Raffaello A, Carraro M, Bernardi P, Pietrangelo L, Boncompagni S, Protasi F, Paolocci N, Reggiani C. Mitochondria can substitute for parvalbumin to lower cytosolic calcium levels in the murine fast skeletal muscle. Acta Physiologica 2024 Sep;240(9):e14208.
• Frigo E, Tommasin L, Lippe G, Carraro M, Bernardi P. The Haves and Have-Nots: The Mitochondrial Permeability Transition Pore across Species. Cells(2023); May 17;12(10):1409.
• Carraro M (corresponding author) and Bernardi P. The mitochondrial permeability transition pore in Ca2+homeostasis. Cell Calcium. (2023); May;111:102719
• Bernardi P, Carraro M, Lippe G. The mitochondrial permeability transition: Recent progress and open questions. The FEBS Journal. (2022); Nov;289(22):7051-7074.
• Carrer A, Laquatra C, Tommasin L, Carraro M (corresponding author). Modulation and Pharmacology of the Mitochondrial Permeability Transition: A Journey from F-ATP Synthase to ANT. Molecules (2021); 26(21):6463.
• Carrer A, Tommasin L, Šileikytė J, Ciscato F, Filadi R, Urbani A, Forte M, Rasola A, Szabò I, Carraro M (co-corresponding author), Bernardi P. Defining the molecular mechanisms of the mitochondrial permeability transition through genetic manipulation of F-ATP synthase. Nature Communications (2021); 10;12(1):4835.
• Sambri I, Massa F, Gullo F, Meneghini S, Cassina L, Carraro M, Dina G, Quattrini A, Patanella L, Carissimo A, Iuliano A, Santorelli F, Codazzi F, Grohovaz F, Bernardi P, Becchetti A, Casari G. Impaired flickering of the permeability transition pore causes SPG7 spastic paraplegia. EBioMedicine (2020), 61:103050.
• Carraro M (co-corresponding author), Jones K, Sartori G, Schiavone M, Antonucci S, Kucharczyk R, di Rago JP, Franchin C, Arrigoni G, Forte M and Bernardi P. The Unique Cysteine of F-ATP Synthase OSCP Subunit Participates in Modulation of the Permeability Transition Pore. Cell Reports (2020); 32(9), 108095.
• Carraro M, Carrer A, Urbani A, Bernardi P. Molecular nature and regulation of the mitochondrial permeability transition pore(s), drug target(s) in cardioprotection. Journal of Molecular and Cellular Cardiology (2020); 144:76-86.
• Carraro M (co-corresponding author), Bernardi P. Measurement of membrane permeability and the mitochondrial permeability transition. Methods in Cell Biology(2020); 155:369-379.
• Antonucci S, Di Sante M, Sileikyte J, Deveraux J, Bauer T, Bround MJ, Menabò R, Paillard M, Alanova P, Carraro M, Ovize M, Molkentin JD, Cohen M, Forte MA, Bernardi P, Di Lisa F, Murphy E. A novel class of cardioprotective small-molecule PTP inhibitors. Pharmacological Research (2020); 151:104548.
• Guo L, Carraro M, Carrer A, Minervini G, Urbani A, Masgras I, Tosatto SCE, Szabò I, Bernardi P, Lippe G. Arginine 8 of yeast subunit e contributes to stability of F-ATP synthase dimers and to generation of the full-conductance megachannel. Journal of Biological Chemistry (2019); 294(28):10987-10997.
• Carraro M, Checchetto V, Szabò I, Bernardi P. F-ATP synthase and the Permeability Transition Pore: Fewer doubts, more certainties. FEBS Letters(2019);593(13):1542-1553.
• Carraro M, Checchetto V, Sartori G, Kucharczyk R, di Rago JP, Minervini G, Franchin C, Arrigoni G, Giorgio V, Petronilli V, Tosatto SCE, Lippe G, Szabó I, Bernardi P. High-Conductance Channel Formation in Yeast Mitochondria is Mediated by F-ATP Synthase e and g Subunits. Cellular Physiology and Biochemistry (2018); 50(5):1840-1855.
• Guo L, Carraro M, Sartori G, Minervini G, Eriksson O, Petronilli V, Bernardi P. Arginine 107 of yeast ATP synthase subunit g mediates sensitivity of the mitochondrial permeability transition to phenylglyoxal. Journal of Biological Chemistry (2018); 293(38):14632-14645.
• Antoniel M, Jones K, Antonucci S, Spolaore B, Fogolari F, Petronilli V, Giorgio V, Carraro M, Di Lisa F, Forte M, Szabó I, Lippe G and Bernardi P. The unique histidine in OSCP subunit of F-ATP synthase mediates inhibition of the permeability transition pore by acidic pH. EMBO Reports (2018);19(2):257-268.
• Carraro M and Bernardi P. Calcium and reactive oxygen species in regulation of the mitochondrial permeability transition and of programmed cell death in yeast. Cell Calcium (2016);60; 102-107.
• Carraro M, Giorgio V, Šileikytė J, Sartori G, Forte M, Lippe G, Zoratti M, Szabò I, Bernardi P. Channel Formation by Yeast F-ATP Synthase and the Role of Dimerization in the Mitochondrial Permeability Transition. Journal of Biological Chemistry (2014);289(23):15980-5.

• Carraro M, Bernardi P. Membrane transport: The mitochondrial permeability transition pore. Encyclopedia of Biological Chemistry: Third Edition, 2021, 2, pp. 997–1007.
• Boscolo Nata F, Tommasin L, Frigo E and Carraro M (corresponding author).Rejuvenating the Mitochondrial Permeability Transition: Perspectives on Structure and Function (24 June 2025), in Elizabeth A. Jonas (ed.), The Oxford Handbook of Mitochondria (online edn, Oxford Academic, 14 July 2021 - ), https://doi.org/10.1093/oxfordhb/9780190932183.013.4.